E-ISSN: 2147-2688
The Role of Magnetic Resonance Imaging for Evaluation of Pancreatic Lipomatosis After Bariatric Surgery
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Original Article
VOLUME: 57 ISSUE: 3
P: 304-309
September 2019

The Role of Magnetic Resonance Imaging for Evaluation of Pancreatic Lipomatosis After Bariatric Surgery

Med Bull Haseki 2019;57(3):304-309
DOI: 10.4274/haseki.galenos.2019.5007
Fatma Kulalı 1
Sevde Nur Emir 1
Aslıhan Semiz-Oysu 1
Yahya Özel 2
Yaşar Bükte 1
1. Sağlık Bilimleri Üniversitesi, Ümraniye Eğitim ve Araştırma Hastanesi, Radyoloji Kliniği, İstanbul, Türkiye
2. Delta Hastanesi, Genel Cerrahi Kliniği, İstanbul, Türkiye
No information available.
No information available
Received Date: 30.12.2018
Accepted Date: 07.05.2019
Publish Date: 20.09.2019
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ABSTRACT

Aim:

To investigate the role of non-contrast magnetic resonance imaging (MRI) and findings of quantitative MRI in the evaluation of pancreatic lipomatosis in patients undergoing bariatric surgery.

Methods:

Pre-operative and post-operative MRI findings and laboratory test results of 44 obese patients, who underwent sleeve gastrectomy, were reviewed retrospectively. Liver craniocaudal length, hepatic and pancreatic region of interest (ROI) ratios at in-phase and out-of phase sequences (in-phase/out-of phase), pancreas/spleen ROI ratio on T2-weighted sequence (T2 ratio) and thickness of subcutaneous fat were estimated. The relationship between pre-operative and postoperative findings was analyzed.

Results:

A total of 44 (41 female, three male) patients with a mean age of 42 were included in the study. Liver length, hepatic and pancreatic in-phase/out-of phase ratios, pancreas/spleen T2 ratio and thickness of subcutaneous fat in the post-operative period were found to be lower than those in the pre-operative period (p<0.05). When pancreas/spleen T2 ratio ≥1 was considered abnormal for the diagnosis of pancreatic lipomatosis, high specificity (100%), positive predictive value (100%) and accuracy (75%) were obtained.

Conclusion:

Non-enhanced MRI with quantitative measurements, including pancreas/spleen T2 ratios, can be performed efficiently for the diagnosis of pancreatic lipomatosis and patient follow-up.

References

1Luo RB, Suzuki T, Hooker JC, et al. How bariatric surgery affects liver volume and fat density in NAFLD patients. Surg Endosc 2018;32:1675-82.
2Ezquerro S, Méndez-Giménez L, Becerril S, et al. Acylated and desacyl ghrelin are associated with hepatic lipogenesis, β-oxidation and autophagy: role in NAFLD amelioration after sleeve gastrectomy in obese rats. Sci Rep 2016;6:39942.
3Ekinci T, Stein MW, Mazzariol FS, et al. Laparoscopic sleeve gastrectomy: Everything the radiologist needs to know. Clin Imaging 2017;43:36-41.
4Lăpădat AM, Jianu IR, Ungureanu BS, et al. Non-invasive imaging techniques in assessing non-alcoholic fatty liver disease: a current status of available methods. J Med Life 2017;10:19-26.
5Dağdeviren M, Altay M, Nalbant E. Pankreatik steatoz: Tanısı ve klinik önemi. J Contemp Med 2017;7:107-12.
6Zhou J, Li ML, Zhang DD, et al. The correlation between pancreatic steatosis and metabolic syndrome in a Chinese population. Pancreatology 2016;16:578-83.
7Pezzilli R, Calculli L. Pancreatic steatosis: Is it related to either obesity or diabetes mellitus? World J Diabetes 2014;5:415-9.
8Smits MM, van Geenen EJ. The clinical significance of pancreatic steatosis. Nat Rev Gastroenterol Hepatol 2011;8:169-77.
9Catanzaro R, Cuffari B, Italia A, et al. Exploring the metabolic syndrome: Nonalcoholic fatty pancreas disease. World J Gastroenterol 2016;22:7660-75.
10van Geenen EJ, Smits MM, Schreuder TC, et al. Nonalcoholic fatty liver disease is related to nonalcoholic fatty pancreas disease. Pancreas 2010;39:1185-90.
11Lesmana CR, Pakasi LS, Inggriani S, et al. Prevalence of non-alcoholic fatty pancreas disease (NAFPD) and its risk factors among adult medical check-up patients in a private hospital: a large cross sectional study. BMC Gastroenterol 2015;15:174.
12Lee JS, Kim SH, Jun DW, et al. Clinical implications of fatty pancreas: correlations between fatty pancreas and metabolic syndrome. World J Gastroenterol 2009;15:1869-75.
13Schwenzer NF, Machann J, Martirosian P, et al. Quantification of pancreatic lipomatosis and liver steatosis by MRI: comparison of in/opposed-phase and spectral-spatial excitation techniques. Invest Radiol 2008;43:330-7.
14Schawkat K, Eshmuminov D, Lenggenhager D, et al. Preoperative evaluation of pancreatic fibrosis and lipomatosis: Correlation of magnetic resonance findings with histology using magnetization transfer imaging and multigradient echo magnetic resonance imaging. Invest Radiol 2018;53:720-7.
15Yuan F, Song B, Huang Z, et al. Quantification of pancreatic fat with dual-echo imaging at 3.0-T MR in clinical application: how do the corrections for T1 and T2* relaxation effect work and simplified correction strategy. Acta Radiol 2018;59:1021-28.
16Yoon JH, Lee JM, Lee KB, et al. Pancreatic steatosis and fibrosis: Quantitative assessment with preoperative multiparametric MR imaging. Radiology 2016;279:140-50.
17Idilman IS, Tuzun A, Savas B, et al. Quantification of liver, pancreas, kidney, and vertebral body MRI-PDFF in non-alcoholic fatty liver disease. Abdom Imaging 2015;40:1512-9.
18Kühn JP, Berthold F, Mayerle J, et al. Pancreatic steatosis demonstrated at MR imaging in the general population: Clinical relevance. Radiology 2015;276:129-36.
19Hui SCN, Wong SKH, Ai Q, Yeung DKW, Ng EKW, Chu WCW. Observed changes in brown, white, hepatic and pancreatic fat after bariatric surgery: Evaluation with MRI. Eur Radiol 2019;29:849-56.
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