Evaluation of Patients Diagnosed with Incidental Gallbladder Cancers After Cholecystectomy
PDF
Cite
Share
Request
Original Article
VOLUME: 57 ISSUE: 2
P: 191 - 194
June 2019

Evaluation of Patients Diagnosed with Incidental Gallbladder Cancers After Cholecystectomy

Med Bull Haseki 2019;57(2):191-194
1. Bolu Abant İzzet Baysal Üniversitesi Tıp Fakültesi, Genel Cerrahi Anabilim Dalı, Bolu, Türkiye
No information available.
No information available
Received Date: 08.10.2018
Accepted Date: 23.12.2018
Publish Date: 27.03.2019
PDF
Cite
Share
Request

ABSTRACT

Aim:

In this study, we evaluated the incidence of incidentel gallbladder cancer patients etiologic factors who underwent cholecystectomy in our clinic.

Methods:

Between January 2010 and December 2017, 3691 patients who underwent cholecystectomy in the General Surgery Department of Bolu Abant İzzet Baysal University Faculty of Medicine were evaluated, retrospectively. Patients were grouped acording to preoperative abdominal ultrasography, blood biochemistry results, age, gender and histopathological results. Tumour, node, metastasis staging of union internationale contre le cancer was used in cancer staging.

Results:

In 3691 patients, gallbladder cancer was detected in 16 patients (0.5%). The pathology specimens of all patients were adenocarcinoma. Two patients had carcinoma insitu, two patients had T1, five patients had T2 and seven patients had T3 tumors.

Conclusion:

In this study the cholecystectomies performed in our clinic showed that the ratio of incidental gallbladder is higher in patients with advanced gallbladder stone and 3 cm or larger than 3 cm. In addition to this, another important condition is the fact that clinical follow-up of pathology specimens and reports of patients who have been prepared and operated preoperatively due to benign gallbladder diseases should not be neglected.

Keywords:
Gallbladder stones, incidental, gallbladder cancer

References

1
Tazuma S. Gallstone disease: Epidemiology, pathogenesis, and classification of biliary stones (common bile duct and intrahepatic). Best Pract Res Clin Gastroenterol 2006;20:1075-83.
2
Halldestam I, Enell EL, Kullman E, Borch K. Development of symptoms and complications in individuals with asymptomatic gallstones. Br J Surg 2004;91:734-8.
3
Kao LS, Kuhr CS, Flum DR. Should cholecystectomy be performed for asymptomatic cholelithiasis in transplant patients? J Am Coll Surg 2003;197:302-12.
4
Lazcano-Ponce EC, Miquel J, Muñoz N, et al. Epidemiology and molecular pathology of gallbladder cancer. CA Cancer J Clin 2001;51:349-64.
5
Stinton LM, Shaffer EA. Epidemiology of gallbladder disease: cholelithiasis and cancer. Gut Liver 2012;6:172-87.
6
Panebianco A, Laforgia R, Volpi A, et al. Predictive factors for incidental gallbladder cancer (IGBC) in patients undergoing cholecystectomy for presumed benign disease. A single-center experience. Ann Ital Chir 2018;89:118-27.
7
Fuks D, Regimbeau JM, Le Treut YP, et al. Incidental gallbladder cancer by the AFC-GBC-2009 Study Group. World J Surg 2011;35:1887-97.
8
Shih SP, Schulick RD, Cameron JL, et al. Gallbladder cancer: the role of laparoscopy and radical resection. Ann Surg 2007;245:893-901.
9
De Aretxabala XA, Roa IS, Mora JP, et al. Laparoscopic cholecystectomy: its effect on the prognosis of patients with gallbladder cancer. World J Surg 2004;28:544-7.
10
Jensen EH, Abraham A, Habermann EB, et al. A critical analysis of the surgical management of early-stage gallbladder cancer in the United States. J Gastrointest Surg 2009;13:722-7.
11
Pawlik TM, Gleisner AL, Vigano L, et al. Incidence of finding residual disease for incidental gallbladder carcinoma: implications for re-resection. J Gastrointest Surg 2007;11:1478-87.
12
Cavallaro A, Piccolo G, Di Vita M, et al. Managing the incidentally detected gallbladder cancer: algorithms and controversies. Int J Surg 2014;12(Suppl 2):108-19.
13
Misra S, Chaturvedi A, Misra NC, Sharma ID. Carcinoma of the gallbladder. Lancet Oncol 2003;4:167-76.
14
Tian YH, Ji X, Liu B, et al. Surgical treatment of incidental gallbladder cancer discovered during or following laparoscopic cholecystectomy. World J Surg 2015;39:746-52.
15
Hamdani NH, Qadri SK, Aggarwalla R, et al. Clinicopathological study of gall bladder carcinoma with special reference to gallstones: our 8-year experience from eastern India. Asian Pac J Cancer Prev 2012;13:5613-7.
16
Vitetta L, Sali A, Little P, Mrazek L. Gallstones and gall bladder carcinoma. Aust N Z J Surg 2000;70:667-73.
17
Goussous N, Maqsood H, Patel K, et al. Clues to predict incidental gallbladder cancer. Hepatobiliary Pancreat Dis Int 2018;17:149-54.