E-ISSN: 2147-2688
Renal Tubular Functions in Children with Primary Nocturnal Enuresis
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Original Article
VOLUME: 50 ISSUE: 1
P: 10-13
March 2012

Renal Tubular Functions in Children with Primary Nocturnal Enuresis

Med Bull Haseki 2012;50(1):10-13
Süleyman Kalman 1
Onur Sakallıoğlu 1
Vural Kesik 2
Faysal Gök 1
1. Gülhane Askeri Tıp Akademisi Çocuk Nefrolojisi Bilim Dalı, Ankara, Türkiye
2. Gülhane Askeri Tıp Akademisi Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Ankara, Türkiye
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ABSTRACT

Introduction:

Theetiology of primarynocturnalenuresis (PNE) is multifactorial. Theeffects of geneticandhormonalfactors, sleepdisorders, andbladderdysfunctionhavebeenclaimed. Theotherfactorsincludeincreasedurineproduction at nightandimpairment of thecircadianrhythm of antidiuretichormone.

Aim:

Toinvestigaterenaltubularfunctions in childrenwith PNE.

Methods:

Fortypatientswith PNE wereincluded in thestudy. Urinedensity, FENa, FEK and TRP wereanalyzed in daytimeandnighttimeurine.

Results:

Themeannighttimeurinedensitywas 1020.12±7.38 andthemeandaytimeurinedensitywas 1013.20±7.11 (p<0.05). Therewasnosignificantdifferencebetweendaytimeandnighttimevalues of FENa (0.50±0.48 vs. 0.38±0.33), FEK (2.78±1.04 vs. 2.76±1.52) and TRP (88.5±2.4 vs 86.7±2.8) (p>0.05).

Conclusion:

Urinedensity in childrenwith PNE waslower at night. However, therewasnodifference in of FENa, FEK and TRP. Furtherstudiesareneeded in ordertoinvestigaterenaltubularfunctions in childrenwith PNE.