ABSTRACT

Aim:

It has been reported that non-alcoholic fatty liver disease (NAFLD) was associated with cholecystectomy and cholecystectomy that may be a risk factor for the development of non-alcoholic fatty liver disease. In this sense, we studied the other risk factors for non-alcoholic fatty liver disease in patients with cholelythiasis.

Methods:

In this study, we included 204 consecutive patients who underwent elective cholecystectomy between June 2011 and January 2014 due to cholelythiasis. We retrospectively evaluated the files of the patients, including operative findings, history, laboratory and radiological imaging findings obtained from the hospital information system and the archived contents of the files.

Results:

There was no significant relationship between the number and size of the stones and hepatic steatosis (p=0.83 and p=0.96, respectively). Besides, there was no statistically significant relationship between gender and hepatosteatosis. In multivariate regression, obesity, type 2 diabetes mellitus (DM) and cholelithiasis were identified as an independent risk factor for NAFLD.

Conclusion:

NAFLD and cholelithiasis are common in the general population and have common risk factors. Obesity, female gender, age, type 2 DM, hypertriglyceridemia, insulin resistance, metobolic syndrome, fast weight loss, and bile stasis are risk factors for cholelithiasis.