Effects of Aspirin Use on Post-operative Complications in Patients Undergoing Bilateral Total Thyroidectomy
PDF
Cite
Share
Request
Original Article
P: 285-289
September 2019

Effects of Aspirin Use on Post-operative Complications in Patients Undergoing Bilateral Total Thyroidectomy

Med Bull Haseki 2019;57(3):285-289
1. Koç Üniversitesi Tıp Fakültesi, Genel Cerrahi Anabilim Dalı, İstanbul, Türkiye
No information available.
No information available
Received Date: 04.03.2019
Accepted Date: 09.04.2019
Publish Date: 20.09.2019
PDF
Cite
Share
Request

ABSTRACT

Aim:

The aim of this study was to assess the effects of preoperative aspirin use on postoperative complications, especially risk of bleeding, in patients undergoing bilateral total thyroidectomy.

Methods:

A total of 201 patients who underwent bilateral total thyroidectomy between 15 August 2016 and 1 February 2019 were included in the study. The patients were divided into two groups: preoperative aspirin group (n=42, 20%) and aspirin-naïve group (n=168, 80%). Parameters, including demographic characteristics, complications and length of hospital stay were compared between the groups.

Results:

Eight (4.4%) patients in aspirin-naïve group and three (7.1%) in preoperative aspirin group had minor hematoma and ecchymosis not requiring any intervention. There was only one patient in aspirin-naïve group (0.5%) who required surgical intervention due to bleeding in the postoperative period, whereas there were not any in the other study group.

Conclusion:

The results of this study showed that aspirin had no significant effect on the development of postoperative complications in patients undergoing bilateral total thyroidectomy. However, large-scale prospective and randomized series are warranted for more accurate and precise results.

References

1Lecompte T, Hardy JF. Antiplatelet agents and perioperative bleeding. Can J Anaesth 2006;53(suppl):S103-12.
2Chassot PG, Marcucci C, Delabays A, et al. Perioperative antiplatelet therapy. Am FamPhysician 2010;82:1484-9.
3Harding J, Sebag F, Sierra M, et al. Thyroid surgery, postoperative hematoma prevention and treatment. Langenbecks Arch Surg 2006;391:169-73.
4Godballe C, Madsen AR, Pedersen HB, et al. Post-thyroidectomy hemorrhage: a national study of patients treated at the Danish departments of ENT Head and Neck Surgery. Eur Arch Otorhinolaryngol 2009;266:1945-52.
5Promberger R, Ott J, Kober F, et al. Risk factors for postoperative bleeding after thyroid surgery. Br J Surg 2012;99:373-9.
6Robert-Ebadi H, Le Gal G, Righini M. Use of anticoagulants in elderly patients: practical recommendations. Clin Interv Aging 2009;4:165-77.
7Snyder SK, Hamid KS, Roberson CR, et al. Outpatient thyroidectomy is safe and reasonable: experience with more than 1,000 planned outpatient procedures. J Am Coll Surg 2010;210:575-82.
8Weiss A, Lee KC, Brumund KT, et al. Risk factors for hematoma after thyroidectomy: results from the nationwide inpatient sample. Surgery 2014;156:399-404.
9Campbell MJ, Mc Coy KL, ShenWT, et al. A multi-institutional international study of risk factors for hematoma after thyroidectomy. Surgery 2013;154:1283-9.
10Randolph GW, Dralle H; International Intraoperative Monitoring Study Group, et al. Electrophysiologic recurrent laryngeal nerve monitoring during thyroid and parathyroid surgery: international standards guideline statement. Laryngoscope 2011;121(Suppl 1):S1-16.
11Bordeaux JS, Martires KJ, Goldberg D, et al. Prospective evaluation of dermatologic surgery complications including patients on multiple antiplatelet and anticoagulant medications. J AmAcad Dermatol 2011;65:576-83.
12Cook-Norris RH, Michaels JD, Weaver AL, et al. Complications of cutaneous surgery in patients taking clopidogrel-containing anticoagulation. J Am Acad Dermatol 2011;65:584-91.
13Alcalay J, Alkalay R. Controversies in perioperative management of blood thinners in dermatologic surgery: continue or discontinue? Dermatol Surg 2004;30:1091-94.
14Savage JR, Parmar A, Robinson PJ. Antiplatelet drugs in elective ENT surgery. J Laryngol Otol 2012;126:886-92.
15Oscarsson A, Gupta A, Fredrikson M, et al. To continue or discontinue aspirin in the perioperative period: a randomized, controlled clinical trial. Br J Anaesth 2010;104:305-12.
16Bass E, Gill P. Report into “on the day cancellations” for plastic surgery in patients who failed to stop their medication. BMJ Qual Improv Rep 2014;3:u204762.w2037.
17Inabnet WB, Shifrin A, Ahmed L, et al. Safety of same day discharge in patients undergoing sutureless thyroidectomy: a comparison of local and general anesthesia. Thyroid 2008;18:57-61.
18Siperstein AE, Berber E, Morkoyun E. The use of the harmonic scalpel vs conventional knot tying for vessel ligation in thyroid surgery. Arch Surg 2002;137:137-42.
19Francis DO, Dang JH, Fritz MA, et al. Antiplatelet and anticoagulation therapy in microlaryngeal surgery. Laryngoscope 2014;124:928-34.
20Lang BH, Yih PC, Lo CY. A review of risk factors and timing for postoperative hematoma after thyroidectomy: is outpatient thyroidectomy really safe? World J Surg 2012;36:2497-502.
21Chen E, Cai Y, Li Q, et al. Risk factors target in patients with post-thyroidectomy bleeding. Int J Clin Exp Med 2014;7:1837-44.
22Rosenbaum MA, Haridas M, McHenry CR. Life-threatening neck hematoma complicating thyroid and parathyroid surgery. Am J Surg 2008;195:339-43.
23Raggio BS, Barton BM, Kandil E, et al. Association of Continued Preoperative Aspirin Use and Bleeding Complications in Patients Undergoing Thyroid Surgery. JAMA Otolaryngol Head Neck Surg 2018;144:335-41.
24Oltmann SC, Alhefdhi AY, Rajaei MH, et al. Antiplatelet and Anticoagulant Medications Significantly Increase the Risk of Postoperative Hematoma: Review of over 4500 Thyroid and Parathyroid Procedures. Ann Surg Oncol 2016;23:2874-82.
25Leyre P, Desurmont T, Lacoste L, et al. Does the risk of compressive hematoma after thyroidectomy authorize 1-day surgery? Langenbecks Arch Surg 2008;393:733-37.
26Burkey SH, van Heerden JA, Thompson GB, et al. Reexploration for symptomatic hematomas after cervical exploration. Surgery 2001;130:914-20.
27Douketis JD, Spyropoulos AC, Spencer FA, et al. Perioperative management of antithrombotic therapy: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 2012;141(2 suppl):e326S-350S.
28Shalom A, Klein D, Friedman T, et al. Lack of complications in minor skin lesion excisions in patients taking aspirin or warfarin products. Am Surg 2008;74:354-57.
29Bartlett GR. Does aspirin affect the outcome of minor cutaneous surgery? Br J Plast Surg 1999;52:214-6.
30Ayyash K, Khammash M, Tibblin S. Drain vs. no drain in primary thyroid and parathyroid surgery. Eur J Surg 1991;157:113-4.
31Schoretsanitis G, Melissas J, Sanidas E, et al. Does draining the neck affect morbidity following thyroid surgery? Am Surg 1998;64:778-80.
Article is only available in PDF format. Show PDF
2024 ©️ Galenos Publishing House