Original Articles

The Prevalence of Diabetes Mellitus Among the Relatives of Type 2 DM Patients - Original Article

  • GÜlden Bayrak
  • Eyüp Koç
  • Murat Suher

Med Bull Haseki 2005;43(1):0-0

Objective:

Our objective was to compare the prevalence of diabetes mellitus (DM) in first degree and second-degree relatives of both type 2 DM patients and a non-diabetic control group.

Material and Method:

We studied 250 patients who were hospitalized in our clinic between 2001-2004. One hundret-seventy two (69%) patients were diabetic, 78 (31%) non-diabetic (control group). The presence of DM in the first and second-degree relatives of both the study and control group was investigated and the result obtained was compared using the Chisquare test.

Results:

The mean age in the study group was 60.6±11.2 (range 28-86); 102 (59.3%) of these were female, 70 (40.7%) were male. The mean age in the control group was 57.7± 10.7 (range 32-90); 46 (59%) were female and 32 (41%) were male patients. The two groups were alike in terms of age, gender and ethnic origin. DM was found in the first and second-degree relatives of 102 (59.9%) cases from the study group, while 22 (28.2%) cases were found from the control group. And this difference was statistically significant (p<0.001). In the study group, 59 (57.3%) of those with positive history had only one affected relative, while 44 (42.7%) had more that one relative affected by DM. In the subgroup analysis: 59 (34.3%) of the patients in the study group and 5 (6.4%) patients in the control group had a sibling affected by DM. The difference was significant (p<0.001). In the other subgroups (children, parents, second degree relatives), more incidents were seen in the study group than the control group; but the difference was not statistically significant.

Conclusion:

The incidence of DM among first degree and second-degree relatives of type II DM patients was higher than the control group. Therefore, it is recommended that the siblings of DM patients should be scanned for glucose metabolic disorder.

Full Text (Turkish)