Original Articles

The Plasminogen Activator Inhibitor-1 Levels in Colon Cancer Patients - Original Article

  • Özgür Kemik
  • Ahu Sarbay Kemik
  • Sefa Tüzün

Med Bull Haseki 2005;43(2):0-0


PAI-1 levels are important plays in metastasis of cancer.


In our study, we investigated of the plasminogen activator inhibitor-1 (PAI-1) in 66 patients with colon cancer and 50 healthy volunteers. We were determined by enzyme linked immunosorbent assay (ELISA) of the PAI-1.


We were found higher of the PAI-1 levels in all patients and in patients with liver metastasis than controls and in patients without liver metastasis.


In conclusion, we suggested that PAI-1 levels may be a useful prognostic marker for colon cancer.

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