Case Report

Fraser Syndrome: A Report of Two Cases


  • Nihal Kılınç
  • Süreyya Demir
  • Bülent Demir

Received Date: 18.03.2015 Accepted Date: 11.04.2015 Med Bull Haseki 2015;53(3):273-276

Fraser syndrome (cryptophthalmos syndactyly syndrome) is a rare autosomal recessive disorder. The main features are cryptophthalmos (hidden eye), ear, nose and skeletal malformations, syndactyly, laryngeal stenosis and malformation of the uro-genital system, lungs, liver, and the central nervous system. Renal anomalies (unilateral/bilateral agenesis) occur in 85% of cases. These anomalies were first documented by Fraser in 1962. In this paper, we present two cases of Fraser syndrome diagnosed after a normal spontaneous vaginal delivery without prenatal follow-up in the light of the literature.

Keywords: Fraser syndrome, cryptophthalmos, syndactyly, autopsy

Full Text (Turkish)