Original Article

The Evaluation of the Distribution and Antimicrobial Susceptibility Profile of the Strains Isolated from Blood Cultures

10.4274/Haseki.1044

  • Gülfem Ece

Med Bull Haseki 2013;51(4):151-156

Aim:

Due to extended life span, invasive procedures, immunosuppressive treatments and surgical procedures have increased the risk of infection risk. Blood cultures are essential in reducing mortality. The aim of our study was to evaluate the distribution and antimicrobial susceptibility profile of the strains isolated from blood cultures at our recently established hospital.

Methods:

The blood cultures sent to the Microbiology Department between 30 May 2012 and 29 January 2013 were evaluated by BacT/alert (Biomerieux, France) system. The identification and antimicrobial susceptibility testing were done using automated Vitek version 2.0 (Biomerieux, France).

Results:

A total of 187 isolates were included. They consisted of 52 (27.8%) gram-negative bacteria, 133 (71.1%) gram-positive bacteria and two (1.06%) C.albicans. The most frequent gram-negative strain was A.baumannii (34.6%); and the most frequent gram-positive strain was MRCoNS. Carbapenem resistance was not detected among the members of the family Enterobacteriaceae. No glycopeptide resistance was detected in gram (+) isolates. 74%of K.pneumoniae strains and 66.7%of E.coli isolates were ESBL positive. 66.7%of A.baumannii strains and 25%of P.aeruginosa isolates were carbapenem-resistant.

Conclusion:

Blood culture results and their antimicrobial susceptibility profiles vary according to different studies. The local data of our recently developed hospital may be important due to variation in data in different regions and time intervals.

Keywords: Blood culture, bacteremia, gram-positive isolate, gram-negative isolate

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